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IRON REGULATORY PROTEIN 2
Descriptors Found:
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DeCS
Descriptor
English
:
Iron Regulatory Protein 2
Descriptor
Spanish
:
Proteína 2 Reguladora de Hierro
Descriptor
Portuguese
:
Proteína 2 Reguladora do Ferro
Tree Number:
D08.811.520.241.300.050.750
D12.776.157.427.374.375.961
D12.776.157.725.437
D12.776.494.750
D12.776.556.579.374.375.962
D12.776.664.962.437
Definition
English
:
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of
aconitate hydratase
. It binds to iron regulatory
elements
found on mRNAs involved in iron
metabolism
and regulates their translation. Its rate of degradation is increased in the presence of IRON.
History Note
English
:
2003; for IRON REGULATORY PROTEIN 2, IRE-BP2 & IRP-2 RNA-BINDING PROTEIN use IRON-REGULATORY PROTEINS (NM) 1995-2002
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
37327
Unique Identifier:
D035942
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS